USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: P00488 USC-OGP 2-DE database:  P00488 P00488 General information about the entry View entry in simple text format Entry name F13A_HUMAN Primary accession number P00488 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Coagulation factor XIII A chain; Short=Coagulation factor XIIIa; EC=2.3.2.13 {ECO:0000269|PubMed:27363989}; AltName: Full=Protein-glutamine gamma-glutamyltransferase A chain; AltName: Full=Transglutaminase A chain; Flags: Precursor;. Gene name Name=F13A1 Synonyms=F13A Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0038: pI=4.86; Mw=62526 SPOT OGP-0236: pI=4.96; Mw=18897 PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0295: pI=5.72; Mw=87145 SPOT OGP-0296: pI=5.65; Mw=86228 PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0621: pI=5.69; Mw=92858 SPOT OGP-0623: pI=5.66; Mw=90293 SPOT OGP-0624: pI=5.73; Mw=87799 PLATELET_6-11 {PLATELET 6-11} Homo sapiens (Human)   map experimental info   PLATELET_6-11 MAP LOCATIONS: SPOT OGP-0860: pI=5.95; Mw=80837 Cross-references UniProtKB/Swiss-Prot P00488; F13A_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name F13A_HUMAN Primary accession number P00488 Secondary accession number(s) Q59HA7 Q8N6X2 Q96P24 Q9BX29 Sequence was last modified on  January 23, 2007 (version 4) Annotations were last modified on  March 15, 2017 (version 208) Name and origin of the protein Description RecName: Full=Coagulation factor XIII A chain; Short=Coagulation factor XIIIa; EC=2.3.2.13 {ECO:0000269|PubMed:27363989}; AltName: Full=Protein-glutamine gamma-glutamyltransferase A chain; AltName: Full=Transglutaminase A chain; Flags: Precursor; Gene name Name=F13A1 Synonyms=F13A Encoded on Name=F13A1; Synonyms=F13A Keywords 3D-structure; Acetylation; Acyltransferase; Blood coagulation; Calcium; Complete proteome; Cytoplasm; Direct protein sequencing; Disease mutation; Glycoprotein; Hemostasis; Metal-binding; Polymorphism; Reference proteome; Secreted; Transferase; Zymogen. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M14539; AAA52489.1; ALT_INIT; mRNA EMBL M14354; AAA52488.1; -; mRNA EMBL M22001; AAA52415.1; -; Genomic_DNA EMBL M21987; AAA52415.1; JOINED; Genomic_DNA EMBL M21988; AAA52415.1; JOINED; Genomic_DNA EMBL M21989; AAA52415.1; JOINED; Genomic_DNA EMBL M21990; AAA52415.1; JOINED; Genomic_DNA EMBL M21991; AAA52415.1; JOINED; Genomic_DNA EMBL M21992; AAA52415.1; JOINED; Genomic_DNA EMBL M21993; AAA52415.1; JOINED; Genomic_DNA EMBL M21995; AAA52415.1; JOINED; Genomic_DNA EMBL M21996; AAA52415.1; JOINED; Genomic_DNA EMBL M21997; AAA52415.1; JOINED; Genomic_DNA EMBL M21998; AAA52415.1; JOINED; Genomic_DNA EMBL M21999; AAA52415.1; JOINED; Genomic_DNA EMBL M22000; AAA52415.1; JOINED; Genomic_DNA EMBL AB208852; BAD92089.1; ALT_INIT; mRNA EMBL AF418272; AAL12161.1; -; Genomic_DNA EMBL AL157775; CAC36886.3; -; Genomic_DNA EMBL AL133326; CAC36886.3; JOINED; Genomic_DNA EMBL AL391420; CAC36886.3; JOINED; Genomic_DNA EMBL AL391420; CAI39797.2; -; Genomic_DNA EMBL AL133326; CAI39797.2; JOINED; Genomic_DNA EMBL AL157775; CAI39797.2; JOINED; Genomic_DNA EMBL AL133326; CAO03607.1; -; Genomic_DNA EMBL AL157775; CAO03607.1; JOINED; Genomic_DNA EMBL AL391420; CAO03607.1; JOINED; Genomic_DNA EMBL BC027963; AAH27963.1; -; mRNA CCDS CCDS4496.1; -; . PIR A35583; EKHUX; . RefSeq NP_000120.2; NM_000129.3; . UniGene Hs.335513; -; . PDB 1EVU; X-ray; 2.01 A; A/B=2-732 PDB 1EX0; X-ray; 2.00 A; A/B=2-732 PDB 1F13; X-ray; 2.10 A; A/B=2-732 PDB 1FIE; X-ray; 2.50 A; A/B=2-732 PDB 1GGT; X-ray; 2.65 A; A/B=2-732 PDB 1GGU; X-ray; 2.10 A; A/B=2-732 PDB 1GGY; X-ray; 2.50 A; A/B=2-732 PDB 1QRK; X-ray; 2.50 A; A/B=2-732 PDB 4KTY; X-ray; 1.98 A; A/B=2-732 PDBsum 1EVU; -; . PDBsum 1EX0; -; . PDBsum 1F13; -; . PDBsum 1FIE; -; . PDBsum 1GGT; -; . PDBsum 1GGU; -; . PDBsum 1GGY; -; . PDBsum 1QRK; -; . PDBsum 4KTY; -; . ProteinModelPortal P00488; -; . SMR P00488; -; . BioGrid 108460; 11; . DIP DIP-377N; -; . IntAct P00488; 9; . MINT MINT-7966415; -; . STRING 9606.ENSP00000264870; -; . BindingDB P00488; -; . ChEMBL CHEMBL4530; -; . DrugBank DB00130; L-Glutamine; . DrugBank DB02340; N-Acetyl-Serine; . iPTMnet P00488; -; . PhosphoSitePlus P00488; -; . BioMuta F13A1; -; . DMDM 119720; -; . OGP P00488; -; . MaxQB P00488; -; . PaxDb P00488; -; . PeptideAtlas P00488; -; . PRIDE P00488; -; . TopDownProteomics P00488; -; . DNASU 2162; -; . Ensembl ENST00000264870; ENSP00000264870; ENSG00000124491; . GeneID 2162; -; . KEGG hsa:2162; -; . UCSC uc003mwv.4; human; . CTD 2162; -; . DisGeNET 2162; -; . GeneCards F13A1; -; . HGNC HGNC:3531; F13A1; . HPA CAB002155; -; . HPA HPA001804; -; . MalaCards F13A1; -; . MIM 134570; gene+phenotype; . MIM 613225; phenotype; . neXtProt NX_P00488; -; . Orphanet 331; Congenital factor XIII deficiency; . PharmGKB PA162; -; . eggNOG ENOG410IFMV; Eukaryota; . eggNOG ENOG410XQEZ; LUCA; . HOGENOM HOG000231695; -; . HOVERGEN HBG004342; -; . InParanoid P00488; -; . KO K03917; -; . OrthoDB EOG091G030K; -; . PhylomeDB P00488; -; . TreeFam TF324278; -; . Reactome R-HSA-114608; Platelet degranulation; . Reactome R-HSA-140875; Common Pathway of Fibrin Clot Formation; . Reactome R-HSA-6785807; Interleukin-4 and 13 signaling; . ChiTaRS F13A1; human; . EvolutionaryTrace P00488; -; . GeneWiki Coagulation_factor_XIII; _A1_polypeptide; -; . GenomeRNAi 2162; -; . PMAP-CutDB P00488; -; . PRO PR:P00488; -; . Proteomes UP000005640; Chromosome 6; . Bgee ENSG00000124491; -; . CleanEx HS_F13A1; -; . ExpressionAtlas P00488; baseline and differential; . Genevisible P00488; HS; . GO GO:0072562; C:blood microparticle; IDA:UniProtKB; . GO GO:0005576; C:extracellular region; TAS:Reactome; . GO GO:0031093; C:platelet alpha granule lumen; TAS:Reactome; . GO GO:0046872; F:metal ion binding; IEA:UniProtKB-KW; . GO GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IDA:UniProtKB; . GO GO:0007596; P:blood coagulation; TAS:Reactome; . GO GO:0072378; P:blood coagulation; fibrin clot formation; IDA:UniProtKB GO GO:0018149; P:peptide cross-linking; IDA:UniProtKB; . GO GO:0002576; P:platelet degranulation; TAS:Reactome; . Gene3D 2.60.40.10; -; 3; . Gene3D 3.90.260.10; -; 1; . InterPro IPR023608; Gln_gamma-glutamylTfrase_euk; . InterPro IPR013783; Ig-like_fold; . InterPro IPR014756; Ig_E-set; . InterPro IPR002931; Transglutaminase-like; . InterPro IPR013808; Transglutaminase_AS; . InterPro IPR008958; Transglutaminase_C; . InterPro IPR001102; Transglutaminase_N; . PANTHER PTHR11590; PTHR11590; 1; . Pfam PF00927; Transglut_C; 2; . Pfam PF01841; Transglut_core; 1; . Pfam PF00868; Transglut_N; 1; . PIRSF PIRSF000459; TGM_EBP42; 1; . SMART SM00460; TGc; 1; . SUPFAM SSF49309; SSF49309; 2; . SUPFAM SSF81296; SSF81296; 1; . PROSITE PS00547; TRANSGLUTAMINASES; 1; .

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